1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity connected to bortezomib, a proteasome inhibitor Employed in the treatment of numerous myeloma. Its synthesis or study is very important for guaranteeing the purity and security of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor inside the synthesis of abiraterone acetate, a drug Employed in the treatment method of prostate cancer by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-10-one): A essential compound within the synthesis of imatinib, a drug that targets specific sorts of cancer, which include Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers which include breast, lung, and prostate most cancers.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are generally intermediates in the synthesis of gemcitabine, an anti-cancer drug. Their analyze is vital for optimizing the production system and guaranteeing higher purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is used to treat breast (3R most cancers, and these intermediates are linked to its manufacturing.
Fulvestrant Intermediates: Fulvestrant is really an estrogen receptor antagonist Employed in the remedy of breast cancer. Different intermediates assist in the synthesis of this drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug helpful in treating cancers like ovarian, breast, and lung cancer.
3. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Utilized in the procedure of colorectal most cancers and little cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is involved with the synthesis of adamantane derivatives, that have many applications, such as antiviral Qualities.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for variety 2 diabetes that inhibits the CAS NO.125700-67-6 enzyme DPP-4 to control blood sugar levels.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with the synthesis of varied gluconic acid derivatives, that happen to be Utilized in foodstuff, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor while in the synthesis of canagliflozin, a medication applied to control form 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).